Key result
Early reports suggested corticotropin (ACTH) provided dramatic results for infantile spasms, though longer-term studies revealed unspecified outcomes.
Population
Infants with infantile spasms (historical context mentions 237 patients from Gibbs)
Design
Review
Authors
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ACTH's early dramatic effects in infantile spasms lack confirmed long-term data; leaves open questions on sustained benefit and warrants prospective evaluation.
Provides a historical overview of infantile spasms and the introduction of corticotropin as a treatment.
C. Harrison Snyder (1967) conducted a review in Infantile spasms. Corticotropin (ACTH) was evaluated. Early reports suggested corticotropin (ACTH) provided dramatic results for infantile spasms, though longer-term studies revealed unspecified outcomes.
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