Key result
Nonalcoholic fatty liver disease was significantly associated with lower serum adiponectin levels (r = -0.22, P=0.008) and higher brachial-ankle pulse wave velocity (P=0.005), especially in females.
Why the study?
Is nonalcoholic fatty liver disease associated with altered serum adiponectin concentrations and brachial-ankle pulse wave velocity?
Population
213 nonalcoholic subjects (67 males, 146 females)
Comparison
Presence of nonalcoholic fatty liver disease… vs Normal group (absence of fatty liver)
Design
Cross-sectional
Authors
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NAFLD may signal higher atherosclerosis risk in females; hypothesis-generating and requires prospective validation before practice change.
Cross-Sectional (n=213)
Is nonalcoholic fatty liver disease associated with altered serum adiponectin concentrations and brachial-ankle pulse wave velocity?
Effect estimate: r = -0.22
p-value: p=0.008
NAFLD is associated with lower serum adiponectin levels and higher arterial stiffness (baPWV), particularly in females, suggesting a link to increased atherosclerosis risk.
Kim et al. (2005) conducted a cross-sectional in Nonalcoholic fatty liver disease (n=213). Nonalcoholic fatty liver disease (NAFLD) vs. Normal group (without fatty liver) was evaluated on Correlation between NAFLD and serum adiponectin level in females (r = -0.22, p=0.008). Nonalcoholic fatty liver disease was significantly associated with lower serum adiponectin levels (r = -0.22, P=0.008) and higher brachial-ankle pulse wave velocity (P=0.005), especially in females.
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