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April 1, 1999HeartOpen Access

Prospective study of health related quality of life before and after coronary artery bypass grafting: outcome at five years

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Key result

Five years after coronary artery bypass grafting, chest pain prevalence increased to 34 of 84 patients compared to 17 of 89 at one year, with unrestricted activities declining from 82-88% to 61-70%.

Why the study?

How does health-related quality of life change between one and five years after coronary artery bypass grafting in male patients under 60?

Population

100 male patients aged < 60 years at time of surgery undergoing coronary artery bypass grafting; 77 had…

Comparison

Coronary artery bypass grafting (CABG) vs 1-year postoperative status

Design

Cohort

Follow-up

5 years

Authors

NCN CaineCystic Fibrosis TrustLSLinda SharplesHeart Failure & TransplantJWJ. WallworkMet Office

Discussion

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Implication

QoL monitoring may be warranted beyond one year post-CABG; leaves open durability of benefits and need for larger prospective studies.

Study Design

Type

Cohort (n=100)

Structured PICO

How does health-related quality of life change between one and five years after coronary artery bypass grafting in male patients under 60?

P
Population
100 male patients aged < 60 years who underwent coronary artery bypass grafting, followed for five years to assess health-related quality of life.
E
Exposure
Coronary artery bypass grafting (CABG)
C
Comparator
1-year postoperative status
O
Outcome
Health related quality of life at five years compared to one year, assessed by Nottingham health profile (NHP)patient reported

While CABG provides early quality of life improvements, physical function and angina symptoms deteriorate by five years, likely reflecting declining graft patency.

Cite This Study

Caine et al. (1999) conducted a cohort in Coronary artery disease requiring bypass grafting (n=100). Coronary artery bypass grafting vs. 1 year post-surgery was evaluated on Health related quality of life (Nottingham health profile) at 5 years compared to 1 year. Five years after coronary artery bypass grafting, chest pain prevalence increased to 34 of 84 patients compared to 17 of 89 at one year, with unrestricted activities declining from 82-88% to 61-70%.

synapsesocial.com/papers/6aa027083dfbbd0b17e6290ahttps://doi.org/10.1136/hrt.81.4.347
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of life after bypass surgery for unstable angina. 5-year follow-up results of a Veterans Affairs Cooperative Study.1991 · 55 citations
  2. 2Prospective study of quality of life before and after coronary artery bypass grafting.1991 · 167 citations
  3. 3Immediate postoperative aspirin improves vein graft patency early and late after coronary artery bypass graft surgery. A placebo-controlled, randomized study.1991 · 174 citations
  4. 4Quality of life in cardiovascular disease.1993 · 90 citations
  5. 5Perceived health: age and sex comparisons in a community.1984 · 218 citations