Key result
Transcatheter aortic valve implantation significantly improved estimated glomerular filtration rate at one month compared to pre-procedure baseline (68.2 vs. 61.0 mL/min, P < 0.01) in high-risk patients with severe aortic stenosis.
Why the study?
Does transcatheter aortic valve implantation improve renal function in patients with aortic stenosis?
Population
70 patients with aortic stenosis undergoing transcatheter aortic valve implantation, mean age 77.6 years…
Comparison
Transcatheter aortic valve implantation (TAVI) vs Pre-procedural baseline
Design
Cohort
Follow-up
Up to 6 months
Authors
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May support renal monitoring post-TAVI in severe AS with CKD; leaves open causal effects pending randomized confirmation.
Cohort (n=70)
No
Does transcatheter aortic valve implantation improve renal function in patients with aortic stenosis?
Absolute Event Rate: 68.2% vs 61%
p-value: p=<0.01
TAVI is associated with an improvement in renal function, particularly in patients with baseline chronic kidney disease, alongside a low incidence of acute kidney injury.
Keleş et al. (2013) conducted a cohort in Severe aortic stenosis (n=70). Transcatheter aortic valve implantation (TAVI) vs. Pre-TAVI baseline was evaluated on Estimated glomerular filtration rate (eGFR) at 1 month (p=<0.01). Transcatheter aortic valve implantation significantly improved estimated glomerular filtration rate at one month compared to pre-procedure baseline (68.2 vs. 61.0 mL/min, P < 0.01) in high-risk patients with severe aortic stenosis.
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