Key result
Black patients experience a higher age-adjusted prevalence of hypertension (57.6% in men, 53.2% in women) and higher hypertension-related mortality rates compared with White patients.
Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“15.9% had the Liddle phenotype and 9.3% had the PA phenotype. Amiloride would therefore have been the appropriate therapy for 1.68-fold more patients than an aldosterone antagonist. This is why simply adding an aldosterone antagonist in patients with uncontrolled hypertension, as recommended in guidelines, would miss an important opportunity for better BP control”
Highlights the disproportionate burden of hypertension and its cardiovascular-renal complications in Black patients, calling for targeted action.
lack patients have the highest age-adjusted prevalence of hypertension (57.6% of men and 53.2% of women), and their blood pressure (BP) is less well controlled despite being more likely to be diagnosed, treated, and treated more intensively.1 In 2017, the death rate from hypertension (per 100 000 population) was 23 in White men, 54.1 in Black men, 18.6 in White women, and 37 in Black women, and BP-related cardiovascularrenal complications (stroke, left ventricular hypertrophy, heart failure, and chronic kidney disease) occur more frequently in Black compared with White patients.2 In sub-Saharan Africa, several studies have similarly demonstrated very high levels of left ventricular hypertrophy, chronic kidney disease, and heart failure related to hypertension.
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Rayner et al. (2021) conducted an editorial in Hypertension. Black race vs. White race was evaluated. Black patients experience a higher age-adjusted prevalence of hypertension (57.6% in men, 53.2% in women) and higher hypertension-related mortality rates compared with White patients.
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