Unilateral Microphthalmia With Congenital Anterior Synechiae and Syndactyly

This report is based on the findings in 2 cases of unilateral microphthalmia in first cousins, girls aged 5½ and 1½ years respectively. In each the anomaly was associated with anterior synechiae which extended from the lesser arterial circle of the iris to the posterior corneal surface. The corneal site of attachment of the iritic membranes was marked by the presence of a hyaline membrane. In addition, in both cases there was partial syndactyly of fingers and toes. REPORT OF CASES The older child, J. C., aged 5½ years, was brought to the clinic of the New York Hospital for an opinion concerning further plastic operations for webbing of fingers and toes and also for an examination of the eyes. The vision in the right eye was 20/200 unimproved and in the left eye was reduced to perception of hand movements. The left eye was moderately microphthalmic. The center of