Key result
Algorithm-based depression care management significantly reduced mortality in older adults with major depression and diabetes mellitus (HR 0.47; 95% CI 0.24-0.91).
Why the study?
Does a depression management program decrease mortality in older adults aged 60 and older with depression and specific medical conditions?
RCT (n=1,226)
randomized
Yes
Does a depression management program decrease mortality in older adults aged 60 and older with depression and specific medical conditions?
Hazard Ratio: 0.47 (95% CI 0.24–0.91)
A primary care depression management program significantly reduced long-term mortality in older adults with major depression and comorbid diabetes mellitus, though not for those with heart disease.
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Supports integrating depression care into primary care for older diabetic adults; extends RCT evidence to long-term mortality benefit in this comorbidity.
Bogner et al. (2016) conducted an RCT in depression and medical comorbidity (n=1,226). algorithm-based care for depression by a care manager vs. usual care was evaluated on mortality (HR 0.47, 95% CI 0.24-0.91). Algorithm-based depression care management significantly reduced mortality in older adults with major depression and diabetes mellitus (HR 0.47; 95% CI 0.24-0.91).
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