February 24, 2005Journal of the American Geriatrics Society
Treatment of Depression Improves Physical Functioning in Older Adults
Key result
The IMPACT collaborative care intervention significantly improved physical functioning at 1 year compared to usual care, with a between-group difference in PCS score of 1.71 (95% CI 0.96-2.46).
Why the study?
Does collaborative care management for depression improve physical functioning in older adults with major depressive disorder?
Population
1,801 patients aged 60 and older with major depressive disorder, mean age 71.2, 65% women, 77% white.
Comparison
Improving Mood: Promoting Access to… vs Usual care.
Design
RCT, randomized
Follow-up
1 year
Authors
Discussion
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Implication
Supports collaborative care integration for late-life depression; extends RCT evidence to physical functioning gains in older adults.
Study Design
Type
RCT (n=1,801)
Multicenter
Yes
Structured PICO
Does collaborative care management for depression improve physical functioning in older adults with major depressive disorder?
P
Population
1,801 patients aged 60 and older with major depressive disorder, followed for 1 year.
I
Intervention
Improving Mood: Promoting Access to Collaborative Treatment (IMPACT) intervention (access for 12 months to a depression clinical specialist who coordinated depression care with their primary care physician).
C
Comparator
Usual care (access to all health services available as part of usual care).
O
Outcome
12-item short form Physical Component Summary (PCS) score and instrumental activities of daily living (IADLs) at 1 year.patient reported
Main Result
Mean Difference: 1.71 (95% CI 0.96–2.46)
Collaborative care management for late-life depression significantly improves physical functioning and self-rated health compared to usual care.
Cite This Study
Callahan et al. (2005) conducted an RCT in major depressive disorder (n=1,801). Improving Mood: Promoting Access to Collaborative Treatment (IMPACT) intervention vs. usual care was evaluated on 12-item short form Physical Component Summary (PCS) score at 1 year (MD 1.71, 95% CI 0.96-2.46). The IMPACT collaborative care intervention significantly improved physical functioning at 1 year compared to usual care, with a between-group difference in PCS score of 1.71 (95% CI 0.96-2.46).