Key result
A 79-year-old woman developed progressive slurring of speech and gait unsteadiness associated with MRI abnormalities following daily administration of 1500 mg of metronidazole.
Case Report (n=1)
Metronidazole administration can cause reversible subacute cerebellar syndrome, myoclonus, and MRI abnormalities.
Metronidazole may induce reversible cerebellar toxicity in elderly patients; this case extends sparse observational reports but leaves incidence and causality open.
Severe neurological adverse effects of metronidazole were recently correlated with brain magnetic resonance imaging (MRI) abnormalities which normalise, along with neurological deficits, upon metronidazole suspension.1,2 We report the case of a diabetic 79-year-old woman, daily medicated with 1500 mg of metronidazole (for chronic foot ulcers), with progressive slurring of speech, gait unsteadiness and …
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Foreid et al. (2009) conducted a case report in Metronidazole-induced neurological adverse effects (n=1). Metronidazole was evaluated on Neurological adverse effects and MRI findings. A 79-year-old woman developed progressive slurring of speech and gait unsteadiness associated with MRI abnormalities following daily administration of 1500 mg of metronidazole.
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