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January 1, 1992Journal of the Chemical Society Chemical Communications

A concise biomimetic total synthesis of (±)-taxodione via a BF 3 ·MeNO 2 promoted cationic cascade annulation

Scott R. Harring Tom Livinghouse

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Abstract

A highly convergent seven-step total synthesis of the antineoplastic agent (±)-taxodione 1 is described which utilizes a cationic cascade cyclization mediated by BF3·MeNO2 complex.

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Harring et al. (1992) studied this question.

synapsesocial.com/papers/6aa038c9c3176e782b2d2666 https://doi.org/10.1039/c39920000502

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