Why the study?
Compression therapy is widely used for edema, but concerns exist regarding its safety in patients with heart failure due to increased venous return potentially increasing pulmonary artery blood pressure.
Does compression therapy improve symptoms and reduce BNP safely in patients with stable chronic heart failure?
Population
101 patients with stable chronic HF initiating compression therapy for lower extremity edema
Design
Retrospective cohort study
Follow-up
1 month
Key result
Compression therapy in patients with stable chronic heart failure significantly reduced NYHA III prevalence from 53.5% at baseline to 32.6% at 1 month (p<0.001), without adverse events.
Authors
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Supports cautious use for edema in stable chronic HF; leaves open confirmation via randomized trials.
Cohort (n=101)
Does compression therapy improve symptoms and reduce BNP safely in patients with stable chronic heart failure?
Absolute Event Rate: 32.6% vs 53.5%
p-value: p=<0.001
Compression therapy appears safe and is associated with improved symptoms and reduced BNP levels in patients with stable chronic heart failure, particularly those with HFpEF.
Nasu et al. (2024) conducted a cohort in Stable chronic heart failure with lower extremity edema (n=101). Compression therapy vs. Baseline was evaluated on New York Heart Association (NYHA) class changes after 1 month (p=<0.001). Compression therapy in patients with stable chronic heart failure significantly reduced NYHA III prevalence from 53.5% at baseline to 32.6% at 1 month (p<0.001), without adverse events.