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July 1, 1996Diabetes

Diabetes and Coronary Heart Disease in American Indians: The Strong Heart Study

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Key result

Diabetes was associated with a higher prevalence of CHD among American Indians, with a greater relative increase in women (prevalence rate 4.6) than in men (1.8) (P=0.002 and P=0.0003).

Why the study?

What is the prevalence of CHD and its association with risk factors such as diabetes among American Indians?

Population

4,549 American Indian adults between 45 and 74 years of age in 13 communities in Arizona, Oklahoma, and…

Design

Cross-sectional

Authors

BHBarbara V. HowardELElisa T. LeeRFRichard R. Fabsitz

Discussion

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Member takes

Overview

May inform sex-stratified CHD risk evaluation in diabetic American Indians; leaves open causal and interventional implications.

Study Design

Type

Cross-Sectional (n=4,549)

Multicenter

Yes

Structured PICO

What is the prevalence of CHD and its association with risk factors such as diabetes among American Indians?

P
Population
4,549 American Indian adults aged 45 to 74 years from 13 communities assessed for the prevalence of coronary heart disease and its associated risk factors.
O
Outcome
Prevalence of coronary heart disease (CHD) and myocardial infarction (MI)hard clinical

Main Result

p-value: P = 0.002 (women) and P = 0.0003 (men)

Diabetes is a highly prevalent and critical risk factor for coronary heart disease among American Indians, with a particularly strong impact on women.

Cite This Study

Howard et al. (1996) conducted a cross-sectional in Coronary heart disease and diabetes (n=4,549). Diabetes and cardiovascular risk factors vs. Absence of diabetes or risk factors was evaluated on Prevalence of definite myocardial infarction (MI) and definite CHD (p=P = 0.002 (women) and P = 0.0003 (men)). Diabetes was associated with a higher prevalence of CHD among American Indians, with a greater relative increase in women (prevalence rate 4.6) than in men (1.8) (P=0.002 and P=0.0003).

synapsesocial.com/papers/6aa03df147b3bd162497594chttps://doi.org/10.2337/diab.45.3.s6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rising Tide of Cardiovascular Disease in American Indians1999 · 470 citations
  2. 2Differences in Risk Factors for Coronary Heart Disease among Diabetic and Nondiabetic Individuals from a Population with High Rates of Diabetes: The Strong Heart Study2012 · 20 citations
  3. 3Cardiovascular Disease Risk Factors among American Indians1995 · 301 citations
  4. 4Hypertension in Adult American Indians1996 · 96 citations
  5. 5Aging and the Prevalence of Cardiovascular Disease Risk Factors in Older American Indians: The Strong Heart Study2007 · 61 citations