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An amelanotic malignant melanoma is difficult to recognize. A lesion without much pigment may be mistaken for an inflammatory condition. Pigmentation occurs more often in malignant melanomas of the skin than in those of the mucous membranes. Diagnosis must be based on histologic examination. Skin- colored lesions of recent development, particularly on the toes, should be routinely subjected to biopsy.
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M Braitman (1959) studied this question.
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