Key result
Neurologic symptoms, consisting of neuralgic amyotrophy and myalgia, occurred in one-third of acute hepatitis E virus infections, with neuralgic amyotrophy occurring more frequently in men.
Why the study?
To assess the prevalence and clinical features of neurologic involvement in patients with acute hepatitis E virus infection in Southern Switzerland.
Population
141 cases of acute HEV infection identified among 1,940 consecutive patients investigated for acute hepatitis E
Comparison
Patients with vs without neurologic symptoms
Follow-up
6 months
Authors
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May prompt HEV testing in neuralgic amyotrophy; extends prior cohorts but leaves causal links and screening open.
Cohort (n=141)
p-value: p=0.03
Neurologic symptoms, particularly neuralgic amyotrophy and myalgia, are common complications occurring in about one-third of acute hepatitis E virus infections.
Ripellino et al. (2019) conducted a cohort in Acute hepatitis E virus (HEV) infection (n=141). Acute hepatitis E virus (HEV) infection was evaluated on Neurologic symptoms (neuralgic amyotrophy and myalgia) (p=0.03). Neurologic symptoms, consisting of neuralgic amyotrophy and myalgia, occurred in one-third of acute hepatitis E virus infections, with neuralgic amyotrophy occurring more frequently in men.
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