Key result
Two young girls with influenza virus A-associated acute necrotizing encephalopathy had a poor prognosis despite aggressive treatment with high-dose corticosteroids and immunoglobulins.
Why the study?
Acute necrotizing encephalopathy is a severe complication of influenza virus infection in children, but its pathophysiology and optimal management remain uncertain.
Population
Two young girls with ANE associated with influenza virus infection
Design
Case report
Authors
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Influenza A-associated ANE in children may portend poor outcomes despite steroids and IVIG; leaves open effective therapies.
Case Report (n=2)
Influenza virus-associated acute necrotizing encephalopathy is a severe complication in children that can result in a poor prognosis despite aggressive immunosuppressive therapy.
Largo et al. (2024) conducted a case report in Acute necrotizing encephalopathy (ANE) associated with influenza virus infection (n=2). Influenza virus A infection was evaluated on Prognosis. Two young girls with influenza virus A-associated acute necrotizing encephalopathy had a poor prognosis despite aggressive treatment with high-dose corticosteroids and immunoglobulins.
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