Key result
During the 2015 outbreak in southern Rajasthan, 39.37% of 1,247 suspected patients tested positive for influenza A H1N1, with significantly higher positivity among females and rural residents.
Why the study?
Swine flu cases resurfaced in January 2015 in southern India as a continuation of the 2009 pandemic, prompting a need to summarize associated clinical and epidemiological factors and estimate the disease burden.
Cross-Sectional (n=1,247)
No
The study highlights the high burden of H1N1 in southern Rajasthan in 2015, particularly affecting young adults, females, and rural populations, with cough and fever as predominant symptoms.
Supports heightened suspicion for H1N1 in rural females; leaves open generalizability beyond 2015 Rajasthan cohort.
Background: Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae (the influenza viruses). Swine flu cases resurfaced in month of January 2015 in Southern region of India which are continuation of pandemic 2009. Aim of this study is to summaries the clinical and epidemiological factors associated with swine flu as well as to estimate the burden of Influenza A H1N1 (Swine Flu) cases.Methods: A complete data of all the patients visiting swine flu OPDs, swine flu wards and ICU were maintained for year 2015. Each patient visiting either the swine flu OPD or the swine flu ward, who was suspected clinically to be H1N1 positive were tested for real time PCR.Results: Out of 1247 samples tested for rt-PCR 491 (39.37%) cases were identified as positive for H1N1. Maximum swine positivity was seen in the age group of 16-30 year i.e. 147 (29.94%). Overall swine positivity was significantly (<0.001) higher in females than male and extremely statistically significant (p<0.0001) higher in rural areas than urban. Cough was the most common clinical symptoms affecting 469(95.52%) patients followed by fever (92.26%) and breathlessness 402(81.87%).Conclusions: Our study will help epidemiologist and clinician to identify epidemiological factors and clinical picture of swine flu.
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Singhal et al. (2019) conducted a cross-sectional in Influenza A H1N1 (Swine flu) (n=1,247). Influenza A H1N1 infection vs. H1N1 negative patients was evaluated on H1N1 positivity rate. During the 2015 outbreak in southern Rajasthan, 39.37% of 1,247 suspected patients tested positive for influenza A H1N1, with significantly higher positivity among females and rural residents.
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