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January 1, 2018Indian Journal of PsychiatryOpen Access

Prevalence and clinical correlates of depression in chronic kidney disease patients in a tertiary care hospital

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Key result

Among patients with chronic kidney disease, the prevalence of major depressive disorder was 44.05%, with a significantly higher prevalence in patients undergoing dialysis compared to other treatments (63.27% vs 17.14%, p<0.0001).

Population

84 chronic kidney disease (CKD) patients in a tertiary care hospital in India

Design

Cross-sectional

Authors

SGShivam GuptaPurdue University West LafayetteMKMallikarjun KarishettiJawaharlal Nehru Medical CollegeBTBheemsain TekkalakiSarojini Naidu Medical College

Discussion

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Implication

Depression affects ~44% of Indian CKD patients; leaves open whether screening improves outcomes.

Study Design

Type

Cross-Sectional (n=84)

Multicenter

No

Structured PICO

P
Population
84 patients with chronic kidney disease (mean age 54 years, 19% female) were evaluated in a cross-sectional study to determine the prevalence and clinical correlates of depression.
O
Outcome
Prevalence of major depression and depressive symptoms

Main Result

Absolute Event Rate: 63.27% vs 17.14%

p-value: p=<0.0001

There is a high prevalence of depression and suicidal ideations among CKD patients, particularly those on dialysis or with high serum creatinine, highlighting the need for routine psychiatric screening.

Limitations

  • Study samples were obtained from a tertiary care hospital, limiting generalizability to the broader population.
  • Comparatively small sample size.
  • The effect of the stage of the disease could not be studied as all patients were in Stage III or more.
  • Cross-sectional design prevents longitudinal or causal conclusions.

Cite This Study

Gupta et al. (2018) conducted a cross-sectional in Chronic kidney disease (n=84). Dialysis vs. Other modes of treatment was evaluated on Prevalence of depression (p=<0.0001). Among patients with chronic kidney disease, the prevalence of major depressive disorder was 44.05%, with a significantly higher prevalence in patients undergoing dialysis compared to other treatments (63.27% vs 17.14%, p<0.0001).

synapsesocial.com/papers/6aa0aa8196c8fbb7e31a03d3https://doi.org/10.4103/psychiatry.indianjpsychiatry_272_18
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1QUALITY OF LIFE IN CHRONIC KIDNEY DISEASE2006 · 88 citations
  2. 2Prevalence of Major Depressive Episode among Patients with Pre-Dialysis Chronic Kidney Disease2011 · 36 citations
  3. 3The evaluation of depression, suicidal ideation and coping strategies in haemodialysis patients with renal failure2011 · 56 citations