Key result
The estimated yearly cost of acute coronary syndrome per patient was 5,478.43 TL according to real clinical practice, compared to 11,319.44 TL when based on guideline recommendations.
Why the study?
Does the real-world clinical practice cost of managing atrial fibrillation and its complications differ from the cost based on guideline recommendations?
Does the real-world clinical practice cost of managing atrial fibrillation and its complications differ from the cost based on guideline recommendations?
Real-world clinical practice costs for managing atrial fibrillation complications differ significantly from guideline-based costs, highlighting deviations from guideline recommendations and the economic burden of the disease.
Answers are grounded in this paper and cite their sources.
Real-world ACS costs lower than guidelines signal care deviations; leaves open outcome impacts in Level 4 data.
OBJECTIVE: To estimate total cost of atrial fibrillation (AF) management concerning acute coronary syndrome, heart failure, stroke and drug related adverse events with respect to clinical practice and available guidelines. METHODS: This cost analysis study was based on identification of total costs related to management of acute coronary syndrome, heart failure, stroke and the drug related adverse events in patients with AF based on standardized questionnaire forms filled by experts according to their daily clinical practice and also to ACCF/AHA/ESC guidelines. Total cost included cost items related to treatment, healthcare resources utilization, and diagnostic test and consultations. RESULTS: The yearly cost of acute coronary syndrome per patient was 5.478.43 TL according to expert's view reflecting real clinical practice whereas it was 11.319.44 TL when calculation was based on recommendations in the guidelines. The average total cost of heart failure was 4.523.74 TL according to expert's view whereas it was 2.925.86 TL based on guidelines. The average total cost of stroke was 5.719.25 TL according to expert's view but 7.931.18 TL based on guidelines. Among drug related adverse events, only those related to cardiac adverse events were estimated to be higher according to expert view as compared to guideline recommendations (288.65 vs. 150.99 TL). CONCLUSIONS: Reflecting the treatment algorithms in the management of AF and related adverse events, our findings seem to emphasize the extra burden on health economics posed by patients suffering from the uncontrolled disease.
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Fak et al. (2012) studied Atrial fibrillation (n=7). Real clinical practice (expert view) vs. Guideline recommendations was evaluated on Yearly cost of acute coronary syndrome per patient (TL). The estimated yearly cost of acute coronary syndrome per patient was 5,478.43 TL according to real clinical practice, compared to 11,319.44 TL when based on guideline recommendations.
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