Key result
Mildly symptomatic dilated and hypertrophic cardiomyopathy were associated with increased left atrial minimum volume compared to healthy controls (94 mL and 86 mL vs 51 mL; P=0.04).
Why the study?
Does cine MR imaging reveal altered biatrial phasic volumetric function in patients with mildly symptomatic dilated and hypertrophic cardiomyopathy compared to healthy subjects?
Observational (n=24)
Does cine MR imaging reveal altered biatrial phasic volumetric function in patients with mildly symptomatic dilated and hypertrophic cardiomyopathy compared to healthy subjects?
p-value: p=0.04
Cine MR imaging demonstrates that mildly symptomatic dilated and hypertrophic cardiomyopathy are associated with left atrial enlargement and reduced cyclic volume changes, as well as compromised right atrial reservoir function.
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Suggests early left atrial remodeling in cardiomyopathy; hypothesis-generating Level 4 data leaves open clinical or prognostic utility.
Järvinen et al. (1996) conducted an observational in Dilated and hypertrophic cardiomyopathy (n=24). Dilated and hypertrophic cardiomyopathy vs. Healthy subjects was evaluated on Left atrial minimum volume (p=0.04). Mildly symptomatic dilated and hypertrophic cardiomyopathy were associated with increased left atrial minimum volume compared to healthy controls (94 mL and 86 mL vs 51 mL; P=0.04).
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