Key result
Percutaneous closure of iatrogenic ASD eliminates right-to-left shunting and improves oxygen saturation to ~98%.
Why the study?
Does percutaneous ASD closure improve symptoms and oxygen saturation in a patient with right-to-left interatrial shunting after transseptal access for catheter ablation?
Case Report (n=1)
No
Does percutaneous ASD closure improve symptoms and oxygen saturation in a patient with right-to-left interatrial shunting after transseptal access for catheter ablation?
Percutaneous device closure of an iatrogenic atrial septal defect causing right-to-left shunting and arterial desaturation after transseptal ablation successfully improved symptoms and oxygenation.
Supports expectant management for most post-transseptal iASDs; leaves open optimal strategies for persistent defects.
Dear Editor, Transseptal access to the left heart is increasingly performed for electrophysiological procedures and for structural heart disease interventions such as balloon mitral valvuloplasty (BMV), left atrial appendage closure (LAAC) and transcatheter mitral valve repair (TMVr). Most of the iatrogenic atrial septal defects (iASDs) close spontaneously, and for those that persist, the majority do
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Chiam et al. (2022) conducted a case report in Iatrogenic atrial septal defect (n=1). Percutaneous ASD closure (Amplatzer septal occluder) was evaluated on Oxygen saturation and symptom improvement. Percutaneous device closure of a symptomatic iatrogenic atrial septal defect with right-to-left shunting successfully eliminated the shunt, improving oxygen saturation from 89% to 98% at 3 months.
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