Key result
Immediate post-TEER iatrogenic ASD closure resolves hypoxia and improves functional status in right heart dysfunction.
Why the study?
The long-term sequelae and management of persistent iatrogenic atrial septal defects following mitral transcatheter edge-to-edge repair are unknown and lack guideline recommendations.
Case Report (n=1)
Immediate iASD closure may resolve hypoxia in select post-TEER patients with right heart dysfunction; leaves open optimal indications and need for prospective trials.
Transcatheter edge-to-edge repair has revolutionized the management of mitral regurgitation in the high surgical-risk population. Iatrogenic atrial septal defects (iASDs) are an obligatory consequence of the procedure. The long-term sequelae of persistent iASDs are unknown but are believed to be dependent on their size, directionality of flow, and underlying hemodynamics. We discuss an uncommon scenario of a post–transcatheter edge-to-edge repair iASD that required immediate closure. (Level of Difficulty: Intermediate.)
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Shetty et al. (2020) conducted a case report in Severe secondary mitral regurgitation and decompensated heart failure (n=1). Immediate iatrogenic atrial septal defect closure was evaluated on Clinical and echocardiographic status post-procedure. Immediate closure of a post-TEER iatrogenic atrial septal defect resolved hypoxia and improved functional status at 30 days in a patient with right heart dysfunction.
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