Key result
Patients with lacunar infarction had significantly lower mean flow velocity in the common carotid artery (25.3 cm/s) compared to those without cerebral infarction (31.1 cm/s, p<0.01).
Why the study?
Does duplex carotid ultrasonography detect differences in carotid flow velocity and plaque in patients with lacunar infarction compared to those without?
Case-Control (n=129)
No
Does duplex carotid ultrasonography detect differences in carotid flow velocity and plaque in patients with lacunar infarction compared to those without?
Patients with lacunar infarction have lower common carotid artery mean flow velocity and a higher incidence of plaque, suggesting more advanced cerebral atherosclerosis.
Answers are grounded in this paper and cite their sources.
May support carotid flow assessment in lacunar infarction; leaves open its value for risk stratification or prevention.
Using duplex carotid ultrasonography, we measured the mean flow velocity in common carotid artery and examined the atherosclerotic lesions (plaque) in 30 patients with lacunar infarction (L group) and 99 patients without cerebral infarction (C group) . L group was diagnosed on clinical symptomatology and infarction size (≤15 mm) by brain CT or MRI. The mean flow velocity (25.3±4.7cm/s) in the L group was significantly lower than that (31.1±7.4cm/s) in the C group. The difference of the mean flow velocities between the L and C groups was considered to be based on the difference of peripheral resistance. In the L group, the mean flow velocity on the affected side was not significantly different from that on unaffected side. Incidence of atherosclerotic lesions (plaque) in the L group was significantly higher than that in the C group.These results suggested that the cerebral atherosclerosis was more advanced in patients with lacunar infarction than in those without brain infarction.
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Furukawa et al. (1996) conducted a case-control in Lacunar infarction (n=129). Lacunar infarction vs. No cerebral infarction was evaluated on Mean flow velocity in common carotid artery (p=<0.01). Patients with lacunar infarction had significantly lower mean flow velocity in the common carotid artery (25.3 cm/s) compared to those without cerebral infarction (31.1 cm/s, p<0.01).
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