Key result
African American patients show similar mortality to Non-Hispanic White patients after type A aortic dissection repair.
Why the study?
It was unknown whether racial disparities exist between African Americans and Non-Hispanic Whites undergoing acute type A aortic dissection repair at a rural tertiary academic medical center.
Does African American race affect outcomes in patients undergoing repair of acute type A aortic dissection compared to Non-Hispanic Whites?
Cohort (n=215)
No
Does African American race affect outcomes in patients undergoing repair of acute type A aortic dissection compared to Non-Hispanic Whites?
Absolute Event Rate: 15.7% vs 13.4%
p-value: p=not significant
African Americans undergo ATAAD repair at a disproportionate rate and present with more comorbidities, but have similar short- and intermediate-term survival compared to Non-Hispanic Whites.
Supports similar short-term ATAAD survival in African Americans despite comorbidities; leaves open questions on access and long-term disparities.
Background To determine if racial disparities exist between African Americans (AA) and Non-Hispanic Whites (NHW) for patients undergoing repair of acute type A aortic dissection (ATAAD) at a rural tertiary academic medical center. Methods There were 215 consecutive AA and NHW patients who underwent ATAAD repair at our institution from 1999 to 2019 included in a retrospective analysis of our Society of Thoracic Surgeons Adult Cardiac Surgery Database. Statistical analysis was performed with a p value of less than .05 considered statistically significant. Results Patients undergoing ATAAD repair were 47% AA despite comprising only 27% of the total population in our region. AAs were significantly younger (54.0 vs. 61.2 years), were more likely to be hypertensive (94.1% vs. 79.7%), had higher creatinine levels (1.7 vs. 1.1 mg/dL), and higher body mass index (30.8 vs. 28.1 kg/m2) (all p values < .006). There were no significant differences in type of repair or intraoperative variables. A logistic regression analysis showed AAs had an increased rate of postoperative acute renal failure not requiring hemodialysis when compared to NHWs (20.8% vs. 10.6%, p value = .042). Thirty-day mortality was not significantly different (15.7% vs. 13.4%) nor was 1-year survival (78% vs. 79%) in AAs and NHWs, respectively. Conclusions Despite AAs having more medical comorbidities at presentation, there were no differences in short- and intermediate-term survival. In our catchment of 1.8 million people, AAs appear to undergo ATAAD repair at a disproportionate rate versus NHWs. These findings may alter strategies for surveillance and prevention of aortic disease in this high-risk population.
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Allman et al. (2021) conducted a cohort in Acute type A aortic dissection (n=215). African American race vs. Non-Hispanic White race was evaluated on 30-day mortality (p=not significant). African American patients undergoing acute type A aortic dissection repair had similar 30-day mortality (15.7% vs 13.4%) and 1-year survival (78% vs 79%) compared to Non-Hispanic White patients.
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