Key result
Waist circumferences above ~93 cm in men and ~90 cm in women identify metabolic syndrome.
Why the study?
What are the optimal waist circumference cut-off points to identify metabolic syndrome components in the Siberian population?
Cross-Sectional (n=9,362)
No
What are the optimal waist circumference cut-off points to identify metabolic syndrome components in the Siberian population?
In a Siberian population aged 45-69, waist circumference cut-offs of 93.3 cm for men and 90.2 cm for women optimally identified the presence of multiple metabolic syndrome components.
Siberian WC cut-offs (93.3 cm men, 90.2 cm women) for ≥2 MS components need confirmation; leaves open applicability to other populations.
Object of research: to determine the cut-off point of waist circumference (WC) identify the components of metabolic syndrome (MS) in a large industrial center of Western Siberia.In the period from 2003 to 2005 in the screening population surveyed 9362 people, including 4268 men (45.6%) and 5094 women (54.4%).The response rate was 61%. The study protocol included a sociodemographic data, measurement of blood pressure (BP), anthropometry (height, weight, WC), the definition of biochemical parameters. Statistical analysis was performed using the package SPSS. To determine the cut-off points of the used ROC model.In the group with ≥2 components of MS cut-off point WC from the men was 93.3 cm (sensitivity 72%, specificity 83%), women – 90.2 cm (sensitivity 72%, specificity 62%).The lowest cut-off point WC marked BP ≥ 130/85 mm Hg for men – 90 cm (sensitivity 66.8%, specificity 58.1%), for women – 86.5 cm (sensitivity 71.0%, specificity 55.7%). The highest cut-off point from the defined patients with diabetes for men was 99.0 cm (sensitivity 61%, specificity 70.2%), for women – cm (sensitivity 64.1%, specificity 65.9%).Conclusions: Cut-off point from the persons with the presence of ≥2 MS components in Siberian population 45–69 years, in accordance with the ROC analysis are 93.3 cm for men and 90.2 cm for women. The lowest cut-off point WC marked BP ≥ 130/85 mm Hg for men – 90 cm, for women – 86.5 cm. The highest cut-off point from the defined patients with diabetes for men was 99.0 cm, for women – 95 cm.
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Симонова et al. (2014) conducted a cross-sectional in Metabolic syndrome (n=9,362). Waist circumference was evaluated on Identification of ≥2 components of metabolic syndrome. In a Siberian population aged 45-69 years, the optimal waist circumference cut-offs to identify ≥2 metabolic syndrome components were 93.3 cm for men and 90.2 cm for women.
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