Key result
Endotoxemia affects ~14% of CABG patients and is linked to increased postoperative infection risk.
Why the study?
Is endotoxemia related to cardiopulmonary bypass associated with an increased risk of postoperative infection in patients undergoing aortocoronary bypass grafting surgery?
Observational (n=57)
No
Is endotoxemia related to cardiopulmonary bypass associated with an increased risk of postoperative infection in patients undergoing aortocoronary bypass grafting surgery?
Endotoxemia during cardiopulmonary bypass is associated with a higher risk of postoperative infections in patients undergoing aortocoronary bypass grafting.
Endotoxemia may identify higher postoperative infection risk after aortocoronary bypass grafting; hypothesis-generating and requires prospective validation before clinical adoption.
The purpose of this study was to examine the prevalence of endotoxemia-supported aortocoronary bypass grafting surgery (ACB), using the endotoxin activity assay (EAA), and to explore the association between endotoxemia and postoperative infection.
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Klein et al. (2011) conducted an observational in Elective aortocoronary bypass grafting surgery (n=57). Endotoxemia vs. Low endotoxin levels was evaluated on Prevalence of endotoxemia. Endotoxemia occurred in 13.5% of patients during aortocoronary bypass grafting and was significantly associated with an increased risk of postoperative infection.
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