Key result
Surgical coronary reimplantation in a 6-week-old infant with ALCAPA improved left ventricular ejection fraction from 13% to 54% at 5 weeks, largely due to resynchronization.
Why the study?
Does surgical coronary reimplantation improve resynchronization and strain recovery in an infant with ALCAPA?
Case Report (n=1)
Does surgical coronary reimplantation improve resynchronization and strain recovery in an infant with ALCAPA?
Answers are grounded in this paper and cite their sources.
Surgical reimplantation of ALCAPA in an infant led to rapid recovery of global LV function, largely driven by resynchronization as quantified by 3D echocardiography and tissue Doppler.
Resynchronization may play a significant role in recovery following surgical reimplantation of anomalous left coronary artery from the pulmonary artery (ALCAPA). Three-dimensional echocardiography and tissue Doppler may quantify this recovery. A 6-week-old infant presented with signs of congestive heart failure due to ALCAPA. Two-dimensional echocardiography showed a severely dilated left ventricular (LV) cardiomyopathy and the presence of ALCAPA was confirmed by catheterization. Three-dimensional echocardiography and tissue Doppler imaging showed severe abnormalities of systolic and diastolic synchrony and decreased contractility with a left ventricular ejection fraction (LVEF) of 13%. The infant underwent surgical coronary reimplantation and was discharged 5 weeks later with an LVEF of 54%. Serial quantitative assessment showed resynchronization and normalization of global LV function following reimplantation. However, segmental contractility improved significantly but remained depressed at discharge. The immediate recovery observed following reimplantation of anomalous coronary may be largely due to resynchronization.
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Fornwalt et al. (2007) conducted a case report in Anomalous left coronary artery from the pulmonary artery (ALCAPA) (n=1). Surgical coronary reimplantation was evaluated on Left ventricular ejection fraction (LVEF) and resynchronization. Surgical coronary reimplantation in a 6-week-old infant with ALCAPA improved left ventricular ejection fraction from 13% to 54% at 5 weeks, largely due to resynchronization.
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