Key result
Recanalization of a chronically occluded LAD resulted in a delayed but complete recovery of left ventricular function, with ejection fraction improving from 32% to 82% over almost 2 years.
Why the study?
Does recanalization of a chronically occluded LAD improve left ventricular function in a patient with severely impaired LV function?
Case Report (n=1)
Does recanalization of a chronically occluded LAD improve left ventricular function in a patient with severely impaired LV function?
Complete recovery of severely impaired left ventricular function may be delayed for almost 2 years following recanalization of a chronic coronary occlusion.
Answers are grounded in this paper and cite their sources.
May support delayed LV recovery after LAD CTO recanalization in severe dysfunction; hypothesis-generating and requires confirmation.
An unusually prolonged course of recovery of severely impaired left ventricular (LV) function (EF 32%) was observed in a patient after recanalization of a chronically occluded LAD. Despite persistent vessel patency, LV function remained depressed for almost 2 years after the percutaneous transluminal coronary angioplasty until complete recovery (EF 82%) could be observed. The possibility of a delayed recovery should be considered when assessing new therapeutic strategies to improve LV function of chronically ischemic myocardium.
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Werner et al. (2003) conducted a case report in Chronically occluded LAD with severely impaired LV function (n=1). Recanalization (percutaneous transluminal coronary angioplasty) was evaluated on Recovery of left ventricular function (ejection fraction). Recanalization of a chronically occluded LAD resulted in a delayed but complete recovery of left ventricular function, with ejection fraction improving from 32% to 82% over almost 2 years.
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