Key result
After CABG, persistently reduced longitudinal function was observed in more than half of pre-operatively viable but dysfunctional segments, with resting systolic strain predicting improvement (AUC 0.753).
Why the study?
Do resting systolic strain and dobutamine stress strain responses predict functional improvement of viable myocardium after CABG in patients with chronic ischaemic heart disease?
Observational (n=57)
Do resting systolic strain and dobutamine stress strain responses predict functional improvement of viable myocardium after CABG in patients with chronic ischaemic heart disease?
Effect estimate: AUC 0.753 (95% CI 0.646-0.860)
Persistently reduced longitudinal function is observed in over half of pre-operatively viable but dysfunctional segments after CABG, suggesting regional remodeling not amendable to revascularization.
No takes yet. Share an insight, caveat, or question.
Persistent post-CABG dysfunction in >50% of viable segments warrants caution in viability assessment; leaves open strain's predictive utility for revascularization decisions.
Rösner et al. (2012) conducted an observational in Chronic ischaemic heart disease (n=57). Coronary artery bypass grafting (CABG) was evaluated on Functional improvement of prior dysfunctional segments (resting strain) (AUC 0.753, 95% CI 0.646-0.860). After CABG, persistently reduced longitudinal function was observed in more than half of pre-operatively viable but dysfunctional segments, with resting systolic strain predicting improvement (AUC 0.753).
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