Key result
Epicardial and pericardial adipose tissue are anatomically and physiologically distinct, making their combined measurement as a single entity conceptually misleading.
Key points are not available for this paper at this time.
Design
Editorial
Highlights the anatomical, embryological, physiological, biomolecular, and clinical differences between epicardial and pericardial adipose tissue, which are often incorrectly treated as identical in imaging studies.
We read the article by Liu et al. (1) with great interest. The investigators carefully stated that because it is difficult to distinguish pericardial from epicardial fat with computed tomography (CT), they measured pericardial adipose tissue by the combination of pericardial fat and epicardial fat. While they recognized this important misclassification, we also noted that they not only technically but conceptually discussed pericardial and epicardial fat as identical to adipose tissue. This appears to be incorrect and misleading. Epicardial and pericardial adipose tissue are clearly different anatomically, embriologically, physiologically, biomolecularly, and clinically (2,3). Epicardial adipose tissue is the fat located between …
No takes yet. Share an insight, caveat, or question.
Iacobellis et al. (2010) reported a letter. Epicardial and pericardial adipose tissue are anatomically and physiologically distinct, making their combined measurement as a single entity conceptually misleading.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: