Key result
A novel technique for quantifying abdominal aortic calcification using unenhanced CT demonstrated minimal interobserver variability, with significant differences occurring in only 2 of 34 patients.
Observational (n=34)
A novel technique for quantifying abdominal aortic calcification using unenhanced CT demonstrated minimal interobserver variability, suggesting its reliability as a standardized method for future studies.
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High interobserver agreement supports standardized AAC quantification on unenhanced CT; leaves open clinical adoption pending validation studies.
Arterial calcification is well recognized as being associated with an increased risk of adverse cardiovascular events. Numerous methods for its quantification have been published, with no consensus on the technique used. In order to assess the reproducibility of a novel technique for quantifying aortic calcification, we measured the interobserver variability between two observers analysing the abdominal aortas of 34 volunteer patients. Using non-contrast abdominal CT images together with commercial imaging software, the quantity of calcium in a pre-determined section of aorta was calculated for each patient, and the difference in values obtained between the two observers compared using a Bland-Altman plot. Minimal interobserver variability was observed, with a significant difference in results occurring for only two patients. This protocol therefore represents a reliable technique that may be applied as a future standard in order to facilitate comparison between studies.
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Bowden et al. (2008) conducted an observational in abdominal aortic calcification (n=34). Measurement of abdominal aortic calcification using unenhanced CT vs. Second observer was evaluated on Interobserver variability. A novel technique for quantifying abdominal aortic calcification using unenhanced CT demonstrated minimal interobserver variability, with significant differences occurring in only 2 of 34 patients.
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