Key result
Diabetes is linked to a ~4-fold higher infection rate and longer hospital stays after CABG.
Why the study?
Does diabetes mellitus increase the risk of adverse postoperative outcomes in patients undergoing CABG?
Cohort (n=717)
No
Does diabetes mellitus increase the risk of adverse postoperative outcomes in patients undergoing CABG?
Absolute Event Rate: 40.1% vs 10.3%
p-value: p=<0.001
Diabetic patients undergoing CABG have a significantly higher risk of postoperative infections and longer hospital stays compared to non-diabetics, though mortality rates are similar.
To describe clinical/laboratory features of patients undergoing coronary artery bypass graft (CABG) in a cardiology reference center. Cohort study; data from patients undergoing CABG (January 2004 to February 2006, n = 717) were evaluated for clinical/laboratory features before, during and after surgery (infections, duration of hospital stay, deaths). Patients were 61.9 ± 11 years old, 67.1% males, 29.6% diabetics. Intraoperatively, diabetics had a central venous catheter placed for a longer period (p < 0.001), but extracorporeal circulation, aortic clamping and total surgery times were similar to those for non-diabetics. Infection occurred in 19.1% of patients (40.1% diabetics vs. 10.3% non-diabetics, p < 0.001). The duration of hospital stay was longer for patients with diabetes vs. non-diabetic patients, but there was no difference in deaths between the two groups (p = 0.797). Patients with diabetes undergoing CABG develop more infectious diseases and stay longer in hospital than non-diabetics.
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Ledur et al. (2011) conducted a cohort in Coronary artery disease requiring CABG (n=717). Diabetes mellitus vs. Non-diabetics was evaluated on Infection (p=<0.001). Patients with diabetes undergoing CABG experienced significantly higher rates of infection compared to non-diabetics (40.1% vs. 10.3%, p<0.001) and longer hospital stays.
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