What is the clinical evidence from this study?

Study design: Observational. Population: Acute respiratory illness (n=3572). Intervention: Viral respiratory infections (Adenovirus, Coe virus, Influenza). Primary outcome: Proportion of respiratory illness admissions associated with specific viral infections.

June 1, 1962Journal of HygieneOpen Access

Coe (Coxsackie A21) virus, para-influenza virus and other respiratory virus infections in the R.A.F., 1958–60

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Key result

Adenovirus and Coe virus infections account for ~34% of acute respiratory admissions in R.A.F. recruits.

n=3,572

Population

R.A.F. recruits and trained men. The 1958-1959 survey included 2,603 admissions to Sick Quarters with…

Design

Cohort

Follow-up

2 months (January to March 1960 for the second survey)

Authors

JMJane McDonaldMontreal Children's Hospital DMD.L. MillerChelsea and Westminster Hospital AZArie J. ZuckermanUniversité Claude Bernard Lyon 1

Discussion

Member takes

Overview

Highlights burden in military recruits; leaves open whether modern surveillance or vaccines should target adenovirus and Coe virus in closed populations.

Study Design

Type

Observational (n=3,572)

Multicenter

Yes

Structured PICO

Population

Over 3,500 Royal Air Force recruits and trained men surveyed between 1958 and 1960 to determine the viral etiology of acute respiratory illnesses.

Outcome

Proportion of respiratory illnesses associated with specific viral infections (influenza A/B, adenovirus, para-influenza, Coe virus)

Respiratory virus infections, particularly adenovirus and Coe virus, were highly prevalent and responsible for a significant proportion of respiratory illness admissions among R.A.F. recruits compared to trained men.

Limitations

Difficulties of interpretation caused by symptomless infection and multiple concurrent infections.
Estimates of illness proportions may not have general application due to variations in age, state of immunity, and other population characteristics.
Volunteers from operational stations were probably not a representative sample.

Cite This Study

McDonald et al. (1962) conducted an observational in Acute respiratory illness (n=3,572). Viral respiratory infections (Adenovirus, Coe virus, Influenza) was evaluated on Proportion of respiratory illness admissions associated with specific viral infections. Adenovirus and Coe virus (Coxsackie A21) infections were major contributors to acute respiratory illness in R.A.F. recruits, accounting for an estimated 26% and 8% of admissions, respectively.

synapsesocial.com/papers/6aa103d29318be7e6b997d46 https://doi.org/10.1017/s0022172400039498

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June 1, 1962Journal of HygieneOpen Access

Coe (Coxsackie A21) virus, para-influenza virus and other respiratory virus infections in the R.A.F., 1958–60

View Full Paper

Ask AI

Bookmark

Key result

Adenovirus and Coe virus infections account for ~34% of acute respiratory admissions in R.A.F. recruits.

n=3,572

Population

R.A.F. recruits and trained men. The 1958-1959 survey included 2,603 admissions to Sick Quarters with…

Design

Cohort

Follow-up

2 months (January to March 1960 for the second survey)

Authors

JMJane McDonaldMontreal Children's Hospital DMD.L. MillerChelsea and Westminster Hospital AZArie J. ZuckermanUniversité Claude Bernard Lyon 1

Discussion

Member takes

Overview

Highlights burden in military recruits; leaves open whether modern surveillance or vaccines should target adenovirus and Coe virus in closed populations.

Study Design

Type

Observational (n=3,572)

Multicenter

Yes

Structured PICO

Population

Over 3,500 Royal Air Force recruits and trained men surveyed between 1958 and 1960 to determine the viral etiology of acute respiratory illnesses.

Outcome

Proportion of respiratory illnesses associated with specific viral infections (influenza A/B, adenovirus, para-influenza, Coe virus)

Limitations

Difficulties of interpretation caused by symptomless infection and multiple concurrent infections.
Estimates of illness proportions may not have general application due to variations in age, state of immunity, and other population characteristics.
Volunteers from operational stations were probably not a representative sample.

Cite This Study

synapsesocial.com/papers/6aa103d29318be7e6b997d46 https://doi.org/10.1017/s0022172400039498

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

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