Key result
Paroxysmal AF is linked to ~72% lower total spectral power during initial supine phase vs controls.
Why the study?
Does sympathovagal balance differ during a supine-standing-supine test in patients with paroxysmal atrial fibrillation compared to healthy controls?
Case-Control (n=54)
No
Does sympathovagal balance differ during a supine-standing-supine test in patients with paroxysmal atrial fibrillation compared to healthy controls?
Absolute Event Rate: 430.7% vs 1558%
p-value: p=0.00002
Patients with paroxysmal atrial fibrillation exhibit altered sympathovagal balance, characterized by decreased total and high-frequency spectral power of heart rate variability, compared to healthy controls.
May indicate autonomic imbalance in paroxysmal AF without altering management; leaves open role of spectral HRV in future risk stratification.
The aim of the study was to assess the sympathovagal balance in group of 27 patients without significant structural heart disease after an attack of atrial fibrillation. The investigation was performed using spectral analysis of heart rate variability during examination under conditions of different orthostatic loads in single phases, called the supine-standing- supine test. The findings were compared with a group of healthy persons. These revealed a significantly decreased total spectral power (430.7 vs 1558.0 ms(2) supine1; 477.6 vs 1042,5 ms(2) standing; 567.5 vs 1948.5 ms(2) supine2), and spectral power of the high frequency spectral component (140.8 vs 619.3 ms(2) supine1; 96.2 vs 203.3 ms(2) standing; 186.3 vs 739.4 ms(2) supine2) in the studied group of patients in comparison with the control group.
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Gałuszka et al. (2004) conducted a case-control in Paroxysmal atrial fibrillation (n=54). History of paroxysmal atrial fibrillation vs. Healthy controls was evaluated on Total spectral power during initial supine position (supine1) (p=0.00002). Patients with paroxysmal atrial fibrillation exhibited significantly decreased total spectral power (430.7 vs 1558.0 ms2, p=0.00002) during the initial supine phase compared to healthy controls.
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