Key result
Heparin and t-AMCHA show variable efficacy in DIC with recovery tied to underlying disease improvement.
Case Report (n=8)
No
In a case series of 8 patients with DIC, treatment efficacy was closely tied to the improvement of the underlying disease, and heparin use may decrease the postmortem detection rate of microthrombi.
Authors
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May warrant prioritizing underlying disease treatment in DIC; leaves open heparin efficacy in prospective studies.
Kurane et al. (1979) conducted a case report in Disseminated Intravascular Coagulation (DIC) (n=8). Heparin and/or t-AMCHA was evaluated on Clinical and hematological improvement / Survival. In 8 cases of DIC, treatment with heparin and/or t-AMCHA showed variable efficacy, suggesting that recovery from DIC is heavily dependent on the improvement of the underlying basic diseases.
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