What question did this study set out to answer?

To evaluate the clinical characteristics, natural disease course, and treatment responses of individuals diagnosed with pityriasis lichenoides.

January 9, 2018Pediatric Dermatology

Pityriasis lichenoides: Long‐term follow‐up study

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Authors

JZJulie B. ZangRockefeller University SCSarah J. CoatesSan Francisco General Hospital JHJing HuangBinghamton University

Discussion

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Overview

Retrospective cohort study reveals prolonged disease duration and limited treatment efficacy in pediatric pityriasis lichenoides, highlighting chronicity and persistent pigmentary changes.

Key Points

To evaluate the clinical characteristics, natural disease course, and treatment responses of individuals diagnosed with pityriasis lichenoides.
Reviewed 75 patients diagnosed with pityriasis lichenoides between 1997 and 2013 at a tertiary referral center.
Conducted long-term telephone follow-up interviews with 46 patients.
Disease duration was significantly shorter in pityriasis lichenoides et varioliformis acuta (35 ± 35 months) than in pityriasis lichenoides chronica (≥78 ± 48 months), with active disease at long-term follow-up persisting in 19% (3/16) versus 82% (23/28), respectively.
No patients progressed to lymphomatoid papulosis or cutaneous T-cell lymphoma, though 10 of 23 active chronica cases had residual pigmentary alterations lasting at least 35 ± 20 months.
The most effective interventions were phototherapy (47% response rate), heliotherapy (33%), topical corticosteroids (27%), and oral antibiotics (25%).

Cite This Study

Zang et al. (2018) studied this question.

synapsesocial.com/papers/6aa11f2fc0e1046e90f7ab8d https://doi.org/10.1111/pde.13396

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January 9, 2018Pediatric Dermatology

Pityriasis lichenoides: Long‐term follow‐up study

View Full Paper

Ask AI

Bookmark

Authors

JZJulie B. ZangRockefeller University SCSarah J. CoatesSan Francisco General Hospital JHJing HuangBinghamton University

Discussion

Member takes

Overview

Retrospective cohort study reveals prolonged disease duration and limited treatment efficacy in pediatric pityriasis lichenoides, highlighting chronicity and persistent pigmentary changes.

Key Points

To evaluate the clinical characteristics, natural disease course, and treatment responses of individuals diagnosed with pityriasis lichenoides.
Reviewed 75 patients diagnosed with pityriasis lichenoides between 1997 and 2013 at a tertiary referral center.
Conducted long-term telephone follow-up interviews with 46 patients.
Disease duration was significantly shorter in pityriasis lichenoides et varioliformis acuta (35 ± 35 months) than in pityriasis lichenoides chronica (≥78 ± 48 months), with active disease at long-term follow-up persisting in 19% (3/16) versus 82% (23/28), respectively.
No patients progressed to lymphomatoid papulosis or cutaneous T-cell lymphoma, though 10 of 23 active chronica cases had residual pigmentary alterations lasting at least 35 ± 20 months.
The most effective interventions were phototherapy (47% response rate), heliotherapy (33%), topical corticosteroids (27%), and oral antibiotics (25%).

Cite This Study

Zang et al. (2018) studied this question.

synapsesocial.com/papers/6aa11f2fc0e1046e90f7ab8d https://doi.org/10.1111/pde.13396

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