Key result
Percutaneous tricuspid leaflet repair shows initial efficacy for early RV reverse remodeling in functional TR.
Why the study?
Given the complex mechanisms leading to right heart failure and RV dysfunction, it is important to understand the real advantages of percutaneous TV treatment, specifically the effect of TR reduction on RV remodeling in functional tricuspid regurgitation.
Does transcatheter tricuspid leaflet repair improve right ventricular remodeling in patients with functional tricuspid regurgitation?
Does transcatheter tricuspid leaflet repair improve right ventricular remodeling in patients with functional tricuspid regurgitation?
Preliminary evidence suggests that transcatheter tricuspid leaflet repair can induce early right ventricular reverse remodeling in patients with functional tricuspid regurgitation, similar to outcomes observed in surgical cohorts.
May support percutaneous tricuspid repair for early RV remodeling in functional TR; hypothesis-generating and requires randomized confirmation.
Clinically significant tricuspid regurgitation (TR) is common and associated with excess mortality. At the same time right ventricular (RV) failure is a complex clinical syndrome that results from many causes, but is often associated with long-term prognosis. Whilst results of isolated tricuspid valve (TV) surgery are often unsatisfactory and limited by the prohibitive risk of most patients, the recent development of percutaneous recovery techniques has opened new scenarios. In consideration of the complexity of the mechanisms that lead to right heart failure and RV dysfunction it is important to understand the real advantages that percutaneous TV treatment can offer, more specifically the effect of TR reduction on RV remodeling in the setting of functional tricuspid regurgitation (fTR).
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Albertini et al. (2022) conducted a review in Functional tricuspid regurgitation. Transcatheter tricuspid leaflet repair was evaluated. Percutaneous tricuspid leaflet repair shows initial efficacy in promoting early right ventricular reverse remodeling in patients with functional tricuspid regurgitation.
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