Key result
Patients with high thrombus burden had a significantly higher DAPT score compared with low thrombus burden patients (p=0.010).
Why the study?
High thrombus burden independently predicts adverse outcomes in AMI, but the predictive role of the DAPT score in estimating intracoronary thrombus burden remained to be evaluated.
Does the DAPT score predict high intracoronary thrombus burden in patients with acute myocardial infarction?
Observational (n=360)
No
Does the DAPT score predict high intracoronary thrombus burden in patients with acute myocardial infarction?
p-value: p=0.010
The DAPT score may serve as a useful clinical tool to predict high intracoronary thrombus burden in patients presenting with acute myocardial infarction prior to percutaneous coronary intervention.
DAPT score may identify AMI patients with high thrombus burden; leaves open whether it improves pre-PCI stratification.
Objectives: High thrombus burden (HTB) was an independent predictor of death, repeat myocardial infarction, and infarct-related artery intervention and stent thrombus in patients with acute myocardial infarction (AMI).This study aimed to evaluate the predictive role of the dual antiplatelet therapy (DAPT) score in the estimation of intracoronary thrombus burden in patients with AMI. Materials and Methods:Between March 2020 and May 2020, 360 consecutive patients admitted with AMI who underwent coronary angiography at the cardiology department of our institution were retrospectively evaluated.The DAPT score has been defined as previously in the DAPT study.The thrombolysis in myocardial infarction (TIMI) thrombus grade was calculated for each patient from the diagnostic angiographic images taken before percutaneous coronary interventions.HTB was defined as TIMI thrombus grades 4 and 5 calculated according to the TIMI thrombus grading scale.The study population was divided into two groups according to their TIMI thrombus grade: low thrombus burden (LTB) (TIMI 0-3) and HTB (TIMI 4 and 5).Results: There were 133 patients (36.9%) in the LT group and 227 patients (63.1%) in the HTB group.Patients with HTB had significantly a higher DAPT score (p=0.010)compared with LTB patients.
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Karaaslan et al. (2022) conducted an observational in Acute Myocardial Infarction (AMI) (n=360). DAPT score was evaluated on High thrombus burden (TIMI thrombus grades 4 and 5) (p=0.010). Patients with high thrombus burden had a significantly higher DAPT score compared with low thrombus burden patients (p=0.010).
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