Key result
High ATRIA score predicts high thrombus burden during STEMI primary PCI with 100% specificity.
Why the study?
The ATRIA score is associated with adverse cardiovascular events, but its relationship with coronary thrombus burden in STEMI patients undergoing PCI is unclear.
Is the ATRIA score associated with high coronary thrombus burden in patients with STEMI undergoing PCI?
Cross-Sectional (n=319)
Is the ATRIA score associated with high coronary thrombus burden in patients with STEMI undergoing PCI?
p-value: p=<.001
The ATRIA score may be a useful predictor of high coronary thrombus burden in patients presenting with STEMI undergoing primary PCI.
May aid thrombus risk stratification in STEMI; leaves open prospective validation before clinical use.
BACKGROUND: The anticoagulation and risk factors in atrial fibrillation (ATRIA) score is associated with adverse cardiovascular events. However, its relationship with coronary thrombus burden is unclear. Therefore, we aimed to investigate the relationship between the ATRIA score and thrombus burden in patients with ST-segment elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention (PCI). MATERIALS AND METHODS: The study was designed as a prospective cross-sectional observational study. Our study included 319 patients who were prospectively admitted with STEMI between January 2021 and April 2022. Patients were divided into 2 groups with low thrombus burden (LTB) (grade <3) and high thrombus burden (HTB) (grade ≥3). ATRIA score was calculated and recorded for all patients. ATRIA scores of both groups were compared. RESULTS: < .001) was significantly higher in the HTB group. In multivariate logistic regression analysis, ATRIA score, glomerular filtration rate, hypertensıon, abciximab usage, and no-reflow were found to be independent predictors of HTB in STEMI patients undergoing primary PCI. In receiver operating characteristic analysis, ATRIA score >4 had a sensitivity of 66.2% and specificity of 95.2%, and ATRIA score >8 sensitivity of 98% and specificity of 100% predicted HTB. CONCLUSION: In this study, we found that thrombus burden may be associated with ATRIA risk score in patients presenting with STEMI.
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Coşkun et al. (2024) conducted a cross-sectional in ST-segment elevation myocardial infarction (STEMI) (n=319). ATRIA score was evaluated on High thrombus burden (grade ≥3) (p=<.001). The ATRIA score was an independent predictor of high thrombus burden in STEMI patients undergoing primary PCI, with a score >8 demonstrating 98% sensitivity and 100% specificity.
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