Key result
Poor physical dimension of health-related quality of life was independently associated with higher mortality among 888 hemodialysis patients over 7 years (303 total deaths).
Why the study?
Are physical and psychological dimensions of health-related quality of life associated with mortality in stable hemodialysis patients?
Cohort (n=888)
Are physical and psychological dimensions of health-related quality of life associated with mortality in stable hemodialysis patients?
In stable hemodialysis patients, poor physical health-related quality of life is a strong independent predictor of mortality, whereas psychological depression is not.
Physical HRQoL may aid risk stratification in hemodialysis; leaves open whether improving it reduces mortality.
BACKGROUND: Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort in Taiwan. METHODS: A total of 888 stable hemodialysis patients were included. Patients completed two questionnaires: the 36-item Short Form Health Survey Questionnaire (SF-36, Taiwan Standard Version 1.0) and the Beck Depression Inventory (BDI, Chinese Version). Mortality outcomes were recorded for a seven-year follow-up period. RESULTS: There were 303 deaths recorded. BDI scores were inversely related to all health-related quality of life (HRQoL) domains (p < 0.001). In the Cox-proportional hazard model, only poor physical dimension of HRQoL was independently associated with higher mortality. CONCLUSION: Poor physical dimension in HRQoL is a strong predictor of mortality among hemodialysis patients in Taiwan. Psychological depression is closely correlated with poor HRQoL but does not predict mortality.
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Peng et al. (2010) conducted a cohort in Hemodialysis (n=888). Poor physical dimension of health-related quality of life was evaluated on Mortality. Poor physical dimension of health-related quality of life was independently associated with higher mortality among 888 hemodialysis patients over 7 years (303 total deaths).
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