Herpes Simplex Virus from Skin Lesions of Myelogenous Leukemia

The various types of clinical response to infection with herpes simplex are becoming increasingly appreciated. Recurrent herpes is a clinical syndrome in the adult that is distinctly different from the primary disease of infants.1Many other manifestations of herpetic infection have been described in recent years. Seidenberg2and Ruchman et al.3demonstrated that one form of Kaposi's varicelliform eruption can be attributed to infection with herpes simplex. Kilbourne and Horsfall4presented evidence that this virus constituted the etiologic agent in two patients with a clinical picture of infectious mononucleosis. Kipping and Downie5recovered herpes simplex virus from variola-like lesions. Morgan and Finland6cultured herpes simplex from the lung at autopsy of a patient with erythema multiforme. Womack and Randall7presented evidence that herpes simplex was the cause of the vesiculobullous lesions in a fatal case of erythema multiforme. Foerster and Scott8described