Key result
Ticlopidine shows no long-term effect on blood viscosity versus placebo in intermittent claudication.
Why the study?
Does ticlopidine reduce blood viscosity in patients with intermittent claudication?
RCT (n=16)
Double-blind
randomized
Does ticlopidine reduce blood viscosity in patients with intermittent claudication?
Long-term treatment with ticlopidine does not reduce blood viscosity in patients with intermittent claudication compared to placebo.
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Ticlopidine offers no viscosity benefit in intermittent claudication; confirms lack of long-term rheological effect in this population.
Fagher et al. (1993) conducted an RCT in intermittent claudication (n=16). ticlopidine vs. placebo was evaluated on blood viscosity. Ticlopidine (500 mg/day) for three years had no long-term effect on blood viscosity compared to placebo in patients with intermittent claudication.
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