Design
Review
Key result
Endothelial dysfunction, driven by oxidative stress and various risk factors, plays a central role in the pathogenesis and progression of atherosclerosis.
Authors
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Supports endothelial dysfunction assessment for atherosclerosis risk stratification; leaves open whether targeted therapies alter outcomes beyond standard risk factor control.
This review highlights the central role of endothelial dysfunction in atherosclerosis and the utility of functional and circulating markers for its detection and monitoring.
Pavel Poredoš (2001) conducted a review in Atherosclerosis. Endothelial dysfunction was evaluated. Endothelial dysfunction, driven by oxidative stress and various risk factors, plays a central role in the pathogenesis and progression of atherosclerosis.