This review of literature is an attempt to summarize different modalities of ozone application in dentistry. Ozone gas has a high oxidation potential and is effective against bacteria, viruses, fungi, and protozoa. It also has the capacity to stimulate blood circulation, platelets, and immune response. Ozone is used in dentistry in gaseous, ozonated water and as ozonated oils. Ozone was shown to be biocompatible and is used in all aspects of dentistry. It has been shown to stimulate remineralization of recent caries-affected teeth and is used as a preventive therapy in caries, root caries, and intracanal irrigants in endodontic treatment. It has been used in treatment of alveolitis, avascular osteonecrosis of the jaw, and herpes virus infection. It also inhibits plaque formation and can be used as an adjuvant in periodontal surgical and maintenance phase. Ozone has also been used in dental unit water line to disinfect water. Advantage of ozone therapy is it is an atraumatic, biologically based treatment. While laboratory studies suggest a promising potential of ozone in dentistry, less number of clinical studies were documented. More number of randomized, controlled trials need to be conducted to determine the precise indications and guidelines to treat various dental pathologies with this promising medical agent.
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Pattanaik et al. (2011) studied this question.
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