Key result
Perioperative optimization and surgical repair achieves 100% 60-day survival in a postinfarction VSD case series.
Why the study?
Postinfarction ventricular septal rupture carries high mortality, and strategies are needed to identify risk factors for poor outcomes and optimize management through medical stabilization, timing of surgery, and mechanical support.
Case Series (n=4)
No
In patients with postinfarction ventricular septal rupture, perioperative optimization with mechanical support and appropriately timed surgical repair can yield favorable short-term survival.
Prompt diagnosis and proactive therapy remain essential in post-MI VSR; leaves optimal surgical timing and percutaneous device role open.
The development of a myocardial infarction ventricular septal rupture is a rare fatal complication, and the surgical repair is the treatment of choice. In most of the scenarios, the operation will be done as an emergency procedure that carries high mortality. Prognosis of these patients depends on prompt echocardiographic diagnosis and the proactive medical and surgical therapy. More recently, various options have been put forward including the timing for surgery, percutaneous closure devices, and the improved outcome with initial stabilization with medical treatment including mechanical support. In this retrospective case series, we are presenting the management of these patients who presented us in different clinical scenarios and trying to identify the risks for the poor outcome and to formulate a strategy to improve the outcome.
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Khazi et al. (2019) conducted a case series in Postinfarction ventricular septal defect (n=4). Perioperative optimization and surgical repair was evaluated on Survival at 60 days. In a case series of four patients with postinfarction ventricular septal defect, perioperative optimization with medical and mechanical support followed by surgical repair resulted in 100% survival at 60 days.
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