What is the clinical evidence from this study?

Study design: Observational. Population: Chronic pulmonary disease (n=64). Intervention: Dynamic exercise vs. Rest. Primary outcome: Change in cardiac index and venous pressure (cardio-venous response).

What question did this study set out to answer?

Investigate changes in cardiac output and cubital venous pressure during dynamic exercise to evaluate the progression of chronic pulmonary disease toward cor pulmonale.

January 1, 1976Japanese Circulation Journal-english EditionOpen Access

Performance of the Right Heart in the Chronic Pulmonary Disease : with Special Reference to the Changes of Cardiac Output and Cubital Venous Pressure during Dynamic Exercise

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Key result

Dynamic exercise protocol for assessing cardio-venous response in chronic pulmonary disease reports no quantitative results.

n=64

Why the study?

Does dynamic exercise alter cardiac index and venous pressure in patients with chronic pulmonary disease compared to those with cardiac disease?

Population

64 patients, including 51 with chronic pulmonary disease and 13 with cardiac disease without pulmonary…

Comparison

Dynamic exercise. vs Resting state (baseline).

Design

Cross-sectional

Authors

STShigeki TakenakaGifu University

Discussion

Member takes

Implication

Method without results leaves open the value of exercise cardio-venous profiling for cor pulmonale risk stratification; prospective studies needed.

Key Points

Investigate changes in cardiac output and cubital venous pressure during dynamic exercise to evaluate the progression of chronic pulmonary disease toward cor pulmonale.
Evaluated 51 patients with chronic pulmonary disease and 13 patients with cardiac disease at rest and during dynamic lower-extremity exercise.
Measured cardiac output using iodine-131 radio-isotope serum albumin radiocardiography and cubital venous pressure using a saline manometer.
Assessed pulmonary function and arterial blood gas parameters at rest and during exercise to correlate with cardio-venous responses.
Simultaneous evaluation of cardiac index and venous pressure successfully established the cardio-venous response profile during exercise.
Hemodynamic changes during physical exertion were evaluated alongside arterial oxygen saturation, blood gas tensions, and spirometric capacities.

Study Design

Type

Observational (n=64)

Structured PICO

Does dynamic exercise alter cardiac index and venous pressure in patients with chronic pulmonary disease compared to those with cardiac disease?

Population

64 patients (51 with chronic pulmonary disease and 13 with cardiac disease) undergoing physiological assessment of cardio-venous response during dynamic exercise.

Exposure

Dynamic exercise (flexion-extension exercise of the lower extremities for 4 minutes at a rate of 36 times a minute).

Comparator

Resting state (baseline).

Outcome

Change in cardiac index (ΔCI) and venous pressure (ΔVP) with exercise ('cardio-venous response').surrogate

The study describes a method to evaluate right heart performance in chronic pulmonary disease using cardio-venous response to exercise, though specific results are not reported in the provided text.

Cite This Study

Shigeki Takenaka (1976) conducted an observational in Chronic pulmonary disease (n=64). Dynamic exercise vs. Rest was evaluated on Change in cardiac index and venous pressure (cardio-venous response). The abstract describes the methodology for assessing cardio-venous response during dynamic exercise in patients with chronic pulmonary disease, but reports no quantitative results.

synapsesocial.com/papers/6aa16c28e808e27a7c4443d3 https://doi.org/10.1253/jcj.40.543

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Implication

Method without results leaves open the value of exercise cardio-venous profiling for cor pulmonale risk stratification; prospective studies needed.

Performance of the Right Heart in the Chronic Pulmonary Disease : with Special Reference to the Changes of Cardiac Output and Cubital Venous Pressure during Dynamic Exercise

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Performance of the Right Heart in the Chronic Pulmonary Disease : with Special Reference to the Changes of Cardiac Output and Cubital Venous Pressure during Dynamic Exercise

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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