Key result
Elevated hs-troponin in critically ill COVID-19 patients is linked to ~6-fold higher in-hospital mortality.
Why the study?
Myocardial involvement among critically ill COVID-19 patients often leads to worse outcomes, but the association between hs-troponin I levels and global longitudinal strain required evaluation.
Do decreased global longitudinal strain and elevated hs-troponin predict the need for mechanical ventilation and in-hospital mortality in critical COVID-19 patients?
Population
65 critical COVID-19 patients at RSUD Dr. Soetomo, Surabaya
Comparison
hs-troponin I levels and global longitudinal strain (GLS)
Design
Prospective cohort study
Follow-up
In-hospital
Authors
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hs-Troponin I–GLS link signals myocardial involvement in critical COVID-19; hypothesis-generating and should not yet change practice.
Cohort (n=65)
No
Do decreased global longitudinal strain and elevated hs-troponin predict the need for mechanical ventilation and in-hospital mortality in critical COVID-19 patients?
Absolute Event Rate: 34.57% vs 5.76%
p-value: p=0.002
In critically ill COVID-19 patients, decreased global longitudinal strain and elevated hs-troponin are significant predictors of the need for mechanical ventilation and in-hospital mortality.
Alsagaff et al. (2024) conducted a cohort in Critical COVID-19 (n=65). Elevated hs-troponin vs. Normal hs-troponin was evaluated on in-hospital mortality (p=0.002). Elevated hs-troponin in critically ill COVID-19 patients was associated with significantly higher in-hospital mortality (34.57% vs. 5.76%, p=0.002).
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