Key result
Apixaban resolves a massive LAA thrombus in a 32-year-old woman with nonrheumatic AF.
Why the study?
Does apixaban resolve massive left atrial appendage thrombus in a patient with non-rheumatic atrial fibrillation?
Case Report (n=1)
Does apixaban resolve massive left atrial appendage thrombus in a patient with non-rheumatic atrial fibrillation?
Apixaban can be successfully used to resolve massive left atrial appendage thrombus in patients with non-rheumatic atrial fibrillation prior to curative ablation.
May support apixaban for massive LAA thrombus in nonrheumatic AF; leaves open need for prospective trials before broader adoption.
A 32-year-old woman with a past medical history of paroxysmal atrial fibrillation, long QT syndrome, and implantation of an automatic iimplantable cardioverter-defibrillator (AICD) following cardiac arrest presented with disabling symptoms of paroxysmal atrial fibrillation due to recurrent AICD shocks. Before curative ablation, transesophageal echocardiography was performed to assess for existing thrombi. This is a rare case of successful resolution with apixaban of a massive left atrial appendage thrombus due to non-rheumatic atrial fibrillation that was successfully treated with apixaban.
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Ghalyoun et al. (2018) conducted a case report in Massive left atrial appendage thrombus due to nonrheumatic atrial fibrillation (n=1). Apixaban was evaluated on Resolution of massive left atrial appendage thrombus. Apixaban successfully resolved a massive left atrial appendage thrombus in a 32-year-old woman with nonrheumatic atrial fibrillation.
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