Key result
Higher gestational age correlates with increased myocardial velocities and lower E/E' ratios on neonatal TDI.
Why the study?
Does tissue Doppler imaging (TDI) enable the measurement of myocardial velocities and E/E' ratios across different gestational ages in neonates?
Observational (n=43)
No
Does tissue Doppler imaging (TDI) enable the measurement of myocardial velocities and E/E' ratios across different gestational ages in neonates?
Tissue Doppler imaging is feasible in preterm and term neonates and demonstrates that myocardial velocities increase and E/E' ratios decrease with advancing gestational age.
Answers are grounded in this paper and cite their sources.
TDI reference values now available by gestational age in neonates; hypothesis-generating for cardiac assessment in preterm infants.
OBJECTIVE: To measure the left and right ventricular myocardial velocities using tissue Doppler imaging (TDI) in the first 24 h of life in neonates. DESIGN: Left and right ventricular peak systolic (S'), early diastolic (E') and late diastolic (A') myocardial velocities were measured using TDI alongside standard echocardiography (including peak diastolic atrioventricular flow, E). E/E' ratio was calculated for both ventricles. SETTING: UK neonatal intensive care unit. PATIENTS: 43 neonates were prospectively recruited into three groups: term (n=16), preterm (30-36 weeks, n=12) and very preterm (<30 weeks, n=15). RESULTS: Myocardial velocities increased with increasing gestation. Right ventricular velocities were significantly greater than left. E/E' ratio decreased with increasing gestation. Left E/E' ratio was higher than right in each group. CONCLUSIONS: TDI is feasible in preterm neonates and enables the acquisition of myocardial velocities. With increasing gestation, higher myocardial velocities and lower E/E' ratios were found. The addition of TDI to standard neonatal echocardiography may provide additional information about cardiac function.
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Negrine et al. (2010) conducted an observational in Neonates (n=43). Tissue Doppler imaging (TDI) was evaluated on Left and right ventricular myocardial velocities and E/E' ratio. Tissue Doppler imaging in neonates during the first 24 hours of life demonstrated that myocardial velocities increased and E/E' ratios decreased with increasing gestational age.
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