Reference ranges for tissue Doppler measures of maternal systolic and diastolic left ventricular function
Key result
Normal pregnancy is associated with modified longitudinal systolic and diastolic function, including a 12% higher lateral S' velocity in the first two trimesters compared to controls (P=0.028).
Why the study?
What are the normal reference ranges for tissue Doppler imaging indices of left ventricular function in normal pregnancy compared to non-pregnant controls?
Population
104 pregnant women at 11-38 weeks of gestation and 19 non-pregnant controls
Comparison
Tissue Doppler imaging and Doppler… vs Non-pregnant controls
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports pregnancy-specific TDI reference values; leaves open prospective validation before clinical adoption.
Study Design
Type
Cross-Sectional (n=123)
Structured PICO
What are the normal reference ranges for tissue Doppler imaging indices of left ventricular function in normal pregnancy compared to non-pregnant controls?
P
Population
123 women, comprising 104 pregnant women at 11-38 weeks of gestation and 19 non-pregnant controls, assessed to construct reference charts for TDI indices.
E
Exposure
Tissue Doppler imaging (TDI) and Doppler echocardiography
C
Comparator
Non-pregnant controls
O
Outcome
Reference charts for TDI indices (transmitral inflow velocities, TDI diastolic and systolic velocities, E:E' ratio, Tei index)surrogate
This study provides normal reference ranges for tissue Doppler imaging indices of left ventricular function during pregnancy, demonstrating modified longitudinal systolic and diastolic function.
Cite This Study
Bamfo et al. (2007) conducted a cross-sectional in Normal pregnancy (n=123). Pregnancy vs. Non-pregnant controls was evaluated on Tissue Doppler imaging (TDI) indices of systolic and diastolic left ventricular function. Normal pregnancy is associated with modified longitudinal systolic and diastolic function, including a 12% higher lateral S' velocity in the first two trimesters compared to controls (P=0.028).