Key result
Fatal cardiac leiomyosarcoma follows malignant uterine fibroid removal by ~10 years with an unclear relationship.
Case Report (n=1)
This case report highlights the diagnostic challenge of determining whether a cardiac leiomyosarcoma is primary or secondary in a patient with a history of a malignant uterine fibroid.
Diagnostic uncertainty persists for cardiac leiomyosarcoma after uterine malignancy; leaves open primary versus late metastatic origin.
Neoplasticinvolvement of the heart is not un- common, but this case presents several features of unusual interest.Almost 10 years after removal ofa malignant fibroid of uterus, the patient died as a result of cardiac involvement by a leiomyosarcoma.During the terminal illness difficulty was encount- ered in reaching a clinical diagnosis and, even after necropsy, a firm opinion as to the relation between the two malignant tumours of smooth muscle has proved impossible.Case Report Early Clinical Features.A 35-year-old multiparous woman was first seen in February 1954, complaining of frequent and increasingly heavy menstrual bleeding.No pelvic abnormality was found at thai time and a normal endometrium was obtained on curettage.The patient's symptoms persisted and on December 6, 1955 laparotomy was performed and showed the uterus to be
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Nicol et al. (1968) conducted a case report in Cardiac leiomyosarcoma (n=1). A 35-year-old woman died from cardiac leiomyosarcoma almost 10 years after removal of a malignant uterine fibroid, with an unclear relationship between the two tumors.
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